This is the first I have heard of your wife's illness. I couldn't quite follow the threads but it looks like you had a car accident that hurt your back then your wife, around this time last year, had complications from anesthesia from a gall stone operation. And since then there have been more surgeries which are causing disorientation issues to arise. My wife is an intensive care RN with a masters degree here in Connecticut who is very involved in autimmune and physiological/psychological trauma treatment. She has actually developed treatments now being used in her hospital to treat psycho/physio related injuries. If you want to email the entire story to me I could show it to her and get you some suggestions by her tthat might help your wife. Sometimes dietary and other remedies that are overlooked by mainstream western medicine can really help.