Joe & Barbara Leffler
Barbara Ellen Leffler was born Nov. 14, 1877 and her brother, Joseph Malton Leffler was born Aug. 23, 1882, both in Indiana. They were both albinos and grew up in the Hoosier Hollow area in Richland County, WI. For many years Barbara and Joe were in the side show in the Ringling Bros. World's Greatest Shows out of Baraboo. After they left the circus, Joe hauled milk with a team of mules in Richland County. Barbara married William Sharp and raised a large family. Barbara died Nov. 25, 1927 and Joe died June 8, 1951.
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[Albino's]
ARE WHITE'S A FIXED ALBINO RACE?
After some research on the web a few years ago I found that there are many types of Albinism, of which the 'Leaky' variety permitted some hair and iris colour and some light tanning, with the production of melanin.
So I concluded that if you put all these types of Albinism on one heap you will find phenomena just like we see in White people today.
This led me to name White’s ‘A fixed Albino race,’ because Albinism is the only way we know of Black people becoming White. We know that the first humans appeared in East Africa and as skin colour is nothing more then a simple adaptation to environment; we believe them to have been brown skinned.
The ones who moved toward the Equator become pitch black. While the one’s who came to Europe became White, as another adaptation to the sunless environment.
Now I find out about yet a different type of Albinism which is hereditary in 25% of the cases. Before, we knew that Albino’s always had normal Black offspring. So this supports my theory that White’s are a fixed Albino race.
Lets not forget that Albinism is found in all ethnicities.
[QUOTE] The child of two albino’s has a change of one-in four to have albinism
Classification
There are two main types of albinism: oculocutaneous albinism (OCA), where melanin pigment is missing in the skin, hair and eyes, and ocular albinism (OA), where the melanin pigment is mainly missing from the eyes, while the skin and hair appear normal. OCA is more common than OA.
Genetics
In ocular-cutaneous albinism, individuals inherit an "albinism gene" from both parents. Where an individual receives one albinism gene and one normal gene, that person will not show outward signs of the condition, but will become a carrier of the recessive gene. Where two carriers of the recessive gene have a child together, that child will have a one in four chance of receiving two albinism genes, and having albinism. The child will have one in four chances of getting neither albinism gene, having normal pigment, and not being a carrier. The child has two in four chances of getting one normal and one albinism gene, having normal pigment but being a carrier. The incidence of carriers in the British population is approximately 1 in 50.
Originally posted by meninarmer
ON EGYPTSEARCH.COM:
TYPES OF ALBINISM
The system for classifying types of albinism is based primarily on which mutated gene caused the disorder rather than how it's manifested. Nonetheless, most types of albinism have some features that distinguish them from each other. Types of albinism include:
*Oculocutaneous albinism.
Oculocutaneous albinism is caused by a mutation in one of four genes. (5) These mutations result in signs and symptoms related to vision (ocular) and those related to skin (cutaneous), hair and iris color.
Oculocutaneous albinism 1 is caused by a mutation in a gene on chromosome 11. Most people with this type of albinism have milky white skin, white hair and blue eyes at birth. Some people with this disorder never experience changes in pigmentation, but others begin to produce melanin during childhood and adolescence. Their hair may become a golden blond or brown. Their skin usually doesn't change color, but it may tan somewhat. The irises may also change color and lose some of their translucence.
Oculocutaneous albinism 2, caused by a mutation in a gene on chromosome 15, is the most common form of the disorder worldwide. It's more common in Sub-Saharan Africans and African-Americans than in other population groups. In people of African descent, the hair is usually yellow, the eyes are blue-gray or tan, and the skin is white at birth. With sun exposure, the skin may over time develop freckles, moles or lentigines. In some cases, the skin may be light brown, and the hair may be brown, auburn, ginger or red.
In Caucasians with oculocutaneous albinism 2, the hair is usually blond, the skin white and the eyes blue at birth. The hair and eyes may darken. The skin usually develops freckles, moles or lentigines.
The rare oculocutaneous albinism 3, caused by a gene mutation on chromosome 9, has been primarily identified in black South Africans. People with this disorder usually have reddish-brown skin, ginger or reddish hair, and hazel or brown eyes.
Oculocutaneous albinism 4, caused by a gene mutation on chromosome 5, is a rare form of the disorder generally presenting signs and symptoms similar to those of type 2. Studies suggest that this type may be one of the most common forms of albinism among people of Japanese and Korean descent.
* X-linked ocular albinism. The cause of X-linked ocular albinism is a gene mutation on the X chromosome. (A woman inherits an X chromosome from each parent. A man inherits an X chromosome from his mother and a Y chromosome from his father.)
In order for a woman to have ocular albinism, she must inherit the gene mutation from both parents. A man with the disorder inherits the gene mutation from his mother. Because there's no corresponding gene on the Y chromosome, the single mutated gene on the X chromosome is sufficient to cause ocular albinism in a man.
People who have ocular albinism have the developmental and functional vision problems of albinism. But a person's skin, hair and eye color are generally in the normal range or slightly lighter for his or her family.
* Hermansky-Pudlak syndrome. Hermansky-Pudlak syndrome is a rare albinism disorder caused by one of at least seven mutated genes. People with this disorder have signs and symptoms like those of oculocutaneous albinism, but they also develop lung and bowel diseases and a bleeding disorder.
* Chediak-Higashi syndrome. Chediak-Higashi syndrome is a rare form of albinism caused by a mutation in a gene on chromosome 1. Signs and symptoms are also similar to those of oculocutaneous albinism. The hair is usually brown or blond with a silvery sheen, and the skin is usually creamy white to grayish. People with this syndrome have a defect with white blood cells that results in a susceptibility to infections. [/QB][/QUOTE]