A 57-year-old man presents to your office with complaints of multiple episodes of severe, unilateral, periorbital headaches over the last two weeks, as well as right now. The patient states that these headaches last approximately one hour and usually occur at night. They wake him from sleep. Sometimes they are accompanied by nasal stuffiness and lacrimation. He denies nausea or vomiting. He noticed that occasional alcohol intake or emotional stress at work precipitates his headache. He tried a large dose of acetaminophen with no significant relief. The patient also complains of periodic episodes of squeezing chest pain after walking 4 to 5 blocks. There is no recent change in the character of the chest pain. His pulse is 72/min, and his blood pressure is 130/80 mm Hg. Physical examination reveals Horner's syndrome on the left side. Which of the following is the most appropriate management for his headache?
(A) Ibuprofen
(B) Prednisone
(C) Ergotamine
(D) Propranolol
(E) Sumatriptan
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