Obviously, space isn't a problem. What I wonder is if the game will be able to find all the files on the disc without Fentible showing up and asking me to replace it. I expect that the four CD copies you mention were copied directly from the original disc images, which I can't do if I copy all the CDs to a single DVD. For instance, the CDs have different volume IDs, and there can obviously only be one volume for one DVD. Also, I'd have a big problem if there are different files with the same names on different discs.
Can anyone tell me what the volume tag is for the DVD edition?
I've used a little too much disc space recently, so I need to clean out my hard disc a little before I start to experiment.
(Edit. I suddenly realized that I was posting with my old, defunct email address. Fixed now. Will this cause a return to the olden days of a zillion spam messages per day?)