I'm sorry and I feel your pain. I agree with the others about the running. It's good for you and a good stress reliever. I wish I could give you an explanation. I've been taking the estinyl for the last 2 weeks and my fsh is sloooowly going down. I hope you find success with it. I keep reminding myself, I'm seeing Check for a reason. This is what he does best. Sending positive thoughts your way!