YES it can fluctuate; mine was 37 and my RE wouldn't even take me as a patient; told me to do egg donation; I was also 40 years old; I was so upset I started reading on the net and bought Fertility Blend at GNC and also went to accupunture and took chinese herbs. Low and behold I was pregnant two months later! I now have a five month old healthy baby boy!! (I also cut down on alcohol and caffeine)