Re the hot spots, that poor baby, having these in addition to the other maladies she's enduring right now. I'm sure you've dealt with these several times in the past, but are now just overwhelmed with all these problems at once...sorry you're going thru this but grateful that you're willing to do this too.
Clean them and clip fur if needed to be able to see the edges of the sores. If you have Betadine, use that, put on with a Q-tip since it can stain...soak the sores well with this disinfectant. If not, try one of the other products being recommended here like original Listerine (yes, it will sting) or dust liberally with a medicated powder, like Gold Bond or Micatan foot powder...most products will "sting" but I believe that you need something that will permit some air to get to the sores too...therefore I wouldn't use something oily. If they are really very sore, you can spray on some 'sunburn spray' that will cause some surface numbing but be sure to avoid eyes and nose with this product.