(Copied over from
original thread.)
Hello VN.
Well, given that you must by now have been using the Clobetasol (Dermovate®)
ointment in combination with an antifungal - either clotrimazole or preferably, intermittent oral fluconazole (Diflucan®) - on the tight part of your foreskin for some three months or so now and seen no response, then I daresay you
could reasonably conclude that circumcision is the last resort.
We shall be most interested to see whether you share Damian's enthusiasm for the results.
Rood has stressed the "inappropriateness" of diagnosing LSA without a biopsy. I have not pressed the point, as whilst technically correct, dermatologists do warn that histopathological diagnoses of skin biopsy specimens are often limited and helpful only to confirm "what you want to see".
In respect of LSA this means they often show some nondescript inflammation that "tends to confirm" the diagnosis - if that is what is clinically suggested. In other words, if the dermatologist thinks it is LSA, then the biopsy either (usually) says "Yes, it looks like LSA" or perhaps says instead "actually, it's perfectly normal". So it may not matter that much whether a biopsy is performed or not - what matters is how it responds to
correct treatment.