Really, the math is straight line.
If a 12 ounce gives you 1,500 to 2,000 shots.
20 OZ divided by 12 OZ gives you 1.7.
1.7 times 1,500 to 2,000 equals 2,500 to 3,300 shots in a 20 OZ.
I use a 24 OZ on a remote coiled setup and figure I get 4,000 shots using 7.0 gr pellets.
There is no reason to use a regulator with such a large CO2 capacity system.
You will get consistent shot after shot to the end of the bottle.