Digital Reflex
--Nipping nail of middle finger cause flexion of terminal phalanx of thumb. Unilaterally---. CNS------: Pyramidal Tract Disease
--Clenched Fist (Levine's) Sign --Holding clenched fist over chest to describe constricting, pressing pain-- CV:--- Angina Pectoris
--de Musset's Sign-- Rhythmic jerking movement of the head--- CV---: Aortic Insufficiency
--Ewart's Sign--- Dullness, bronchial breathing, bronchophony over the angle of the left scapula.--- CV:--- Pericardial effusion
---Hamman's Sign ---Crunching sound synchronous with heartbeat.--- CV:--- Mediastinal Emphy-sema,--- Pneumopericardium
---Hill's Sign ---Exaggerated femoral artery systolic pressure (60 to 100 mm Hg higher) over brachial systolic pressure.--- CV--- Aortic Insufficiency
---Homan's Sign--- Pain in back of calf or knee when foot is dorsiflexed.---- CV:--- Thrombosis in veins of calf
--Kussmaul's Sign-- Paradoxical increase in jugular venous distension when patient inspires.---- CV----: Cardiac Tamponade
--Osler's Sign-- Painful erythematous swellings in skin and subcutaneous tissues of hands and feet.--- CV---: Endocarditis
---Joffroy's Sign ---No forehead wrinkling when the eyeballs are rolled upward.---- Endocrine:--- Grave's Disease
---Möbius Sign --Impaired ocular convergence (accommodation)--- Endocrine:-- Grave's Disease
--Stellwag's ---Infrequent and incomplete blinking.---- Endocrine:--- Grave's Disease
--Kestenbaum's Sign --Decrease in number of arterioles crossing optic disk margins----. Eye:---- Optic Atrophy
---Marcus Gunn Pupillary Sign ---Flashlight swung from one eye to the other eye, then both pupils dilate (when they should constrict).--- Eye:- Cataract,---- optic nerve defects
---Cullen's Sign--- Periumbilical darkening of the skin--- GI:-- Intraperitoneal hemorrhage, from hemorrhagic pancreatitis or- ectopic pregnancy
---Grey Turner's Sign--- Local discoloration of the skin of the loins--- GI:--- Acute hemorrhagic pancreatitis
---Groove Sign ---Firm nodes in groin above and below inguinal ligament, with a groove along the ligament----. GI:--- Lymphogranuloma Venereum
---Kehr's Sign ---Violent pain in the left shoulder GI: Ruptured Spleen
--Puddle Sign ---Patient gets on all fours, and palpating at one end allows auscultation at the other end of the abdomen. Stethoscope moves from most dependent position gradually contralaterally. GI: Ascites
---Rovsing's Sign --Pain in right abdomen at McBurney's Point when pressure is exerted on left abdomen.--- GI---: Appendicitis
--Bárány's Sign ---Irrigate ear with cold water: should lead to nystagmus on opposite side.
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