I had severe m/s with my two prior PGs, too, but nothing like with my third. Nothing worked, I couldn't leave the house. The only thing that helped was Zofran. And with the Zofran came severe constipation, but it was better than the constant puking. I'd only take a half of the Zofran so the constipation wouldn't be as bad, and that still helped a ton.
Hugs to you. I know how miserable it is to feel like that. ((((()))))