Duloxetine is believed to potentiate both serotonin and noradrenaline in the brain and the spinal cord, impacting nerve signaling. Based on pre-clinical studies, duloxetine is a balanced and potent reuptake inhibitor of serotonin and noradrenaline. While the mechanism of action of duloxetine in humans is not fully known, scientists believe its effect on improvement of depressive symptoms and pain perception is due to increasing the activity of serotonin and noradrenaline in the central nervous system.
For more information, contact:
Public Relations Unit, Shionogi & Co., Ltd.
06-6209-7885 (Osaka) or 03-3406-8164 (Tokyo)
Corporate Affairs, Eli Lilly Japan K.K.
Miyuki Watanabe at 078-242-9192
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