David P.J. Osborn, Ph.D., and colleagues at the Royal Free and University College Medical School, London, selected 46,136 individuals with severe mental illness (including schizophrenia, schizoaffective disorder, bipolar disorder and delusional disorder) and 300,426 without mental illness from a nationally representative database in the United Kingdom. The researchers compared the two group's death rates from coronary heart disease, stroke and the seven most common types of cancer in the United Kingdom?respiratory, colorectal, breast, prostate, stomach, esophageal and pancreatic cancer. "We chose to study death rates rather than incidence rates, because mortality is the most robust outcome since it includes diagnoses made post-mortem," the authors write.
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