Demerol has cardiac arrest listed as an ADR.
Demerol and Zoloft can cause serotonin syndrome. The following is re cardiac arrest in serotonin syndrome.
Page 86 of Pharmacotherapy
"...Cardiac arrest, coma and multiorgan system failure have been reported as consequences of serotonin syndrome. 123..."
References on Page 90 of Pharmacotherapy (scroll down the above link)
"123. Boyer EW...The Serotonin Syndrome..." - difficult to read the entire title
but assuming it refers to the book mentioned in this google search which lists links below as:
"NEJM -- The Serotonin Syndrome
The Serotonin Syndrome Basu D., Gillman P. K., Gnanadesigan N., Espinoza R. T., Smith R. L., Claassen J. A.H.R., Gelissen H. P.M.M., Boyer E. W., Shannon M. ...
content.nejm.org/cgi/content/full/352/11/1112 - Similar
by EW Boyer - 2005 - Cited by 252 - Related articles
Selective serotonin reuptake inhibitor poisoning
Boyer, EW, Shannon, M. The serotonin syndrome. N Engl J Med 2005; 352:1112. .... of Torsades de Pointes (TdP) with cardiac arrest (abstract #86). ...
www.uptodate.com/patients/content/topic.do?topicKey... - Cached - Similar
Advanced Emergency Nursing Journal
This dysfunction could take the role of cardiac or respiratory arrest, status epilepticus, .... Boyer, ew, & Shannon, M. (2005). The serotonin syndrome. ...
journals.lww.com/.../Management_of_Serotonin_Syndrome__Clinical.4.aspx - Similar [In the previous message on the forum, you can see "autonomic dysfunction" as a symptom of Serotonin Syndrome listed in the paragraph commencing Monitor Closely (under the heading Zoloft and Demerol Interactions) from drugs.com]
Informa Pharmaceutical Science - Clinical Toxicology - 45(8):961 ... No evident explanation for this sudden cardiac arrest was found; .... Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med 2005; 352: 111220 ...
www.informapharmascience.com/doi/pdf/10.../15563650701438847 - Similar
by C Daubin - 2007 - Cited by 2 - Related articles..."
Critical Care | Full text | Bench-to-bedside review: Mechanisms ...
6 Dec 2007 ... Management of the serotonin syndrome involves the removal of the precipitating drugs, ... elevation of serum creatine kinase and hyperkalemia resulting in cardiac arrest, .... Boyer EW, Shannon M: The serotonin syndrome. ...
ccforum.com/content/11/6/236 - Cached - Similar
by F Eyer - 2007 - Cited by 1 - Related articles - All 6 versions..."
and more.
