Warnings & Precautions (page 4) of OxyContin rxlist
"...Respiratory Depression
Respiratory depression is the chief hazard from oxycodone, the active ingredient in OxyContin® , as with all opioid agonists. Respiratory depression is a particular problem in elderly or debilitated patients, usually following large initial doses in non-tolerant patients, or when opioids are given in conjunction with other agents that depress respiration..."
Side Effects (Page 3) re respiratory depression and respiratory ARREST
"Serious adverse reactions which may be associated with OxyContin Tablet therapy in clinical use are those observed with other opioid analgesics, including respiratory depression, apnea, respiratory arrest, and (to an even lesser degree) circulatory depression, hypotension, or shock (see OVERDOSAGE)..."
