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Pravastatin but Not Atorvastatin Treatment Impairs Cognitive Function - in rats

September 25 2013 at 1:26 PM
Anonymous 

Chronic Pravastatin but Not Atorvastatin Treatment Impairs Cognitive Function in Two Rodent Models of Learning and Memory

 

 

Paper

The paper Chronic Pravastatin but Not Atorvastatin Treatment Impairs Cognitive Function in Two Rodent Models of Learning and Memory by Stuart SA, Robertson JD, Marrion NV, Robinson ESJ is published in PLOS ONE : e75467. doi:10.1371/journal.pone.0075467http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075467

What are statins used for?

Statins are medicines that are prescribed to help protect healthy, but high-risk, people from heart disease and to prevent repeated problems in people who have already had a heart attack, a stroke or peripheral artery disease.

How do statins work?

The cells in our body make a fatty substance called cholesterol. The liver makes the cholesterol mostly from the saturated fats in the food we eat. Cholesterol plays a vital role in how every cell works, throughout the body, and the body uses cholesterol to make other vital chemicals. However, having too much cholesterol in the blood can increase your risk of getting heart and circulatory disease. Statins reduce the amount of cholesterol produced by cells all over our body. This forces them to get their supply by removing it from the bloodstream. So this lowers the blood cholesterol level.

Source: British Heart Foundation


 
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  1. link between commonly prescribed statin and memory impairment - Anonymous on Sep 25, 2013, 1:29 PM
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