My personal opinion is:
Doc/Margo/Tom/Jessica/Ben- I don't like what they are doing to Tom and Margo, or Ben and Jessica for that matter, however I like the story. Its gotten more interesting in my opinion. I love seeing our beloved super couples in a real storyline.
Matie- These two belong together, forget Simon, he left the first time. Mike never really left Katie although he didn't believe her. When Terri comes back I hope these two hook up again and finally get married.
Aliris- I love how these two are engaged, but if spoilers are true here then I will possibly quit watching.
HEM- same goes for them.
Hal/Emily/Nikki- I don't like how Em and Nikki don't get along because I don't want Hal stuck in the middle here. But I'm interested to see how this will all play out.
Prosanna- I love these two together and they should hook up. Today was so sweet between them!
Jendan- I hope nothing causes these two to lose faith in one another and separate permanently.