A stroke in 1983.
His car plunged into the icy waters of Salem's harbor during a police chase in 1984
Marlena shot him, and he fell from a catwalk as the building caught fire in 1985 (he also had a brain tumor)
In 1991, he was presumed to have died in another fire and cave collapse.
In 1994, his car erupted into a fireball after being shot at by John.
Also in 1994, he drowned near Maison Blanche.
In 1996, he died in a plane explosion.
Again, in 1996, he was blown up and buried under collapsing tunnel during confrontation with Rachel Blake. This was his last depicted "death" until 2007.
In 2002, Andre DiMera (posing as Tony) claimed that his uncle had died from injuries sustained from a car crash in Monte Carlo.
In 2004, when Marlena and the presumed dead Salem Stalker victims found a blackened, unrecognizable corpse on Melaswen, Andre (posing as Tony) claimed it was Stefano. Andre said he had killed Stefano by draining his blood so Andre could cure his own blood disease.
In 2007, his death was faked once again. As a setup by the Salem P.D., Steven "Patch" Johnson appeared to stab Stefano to death, but he was drugged and a fake funeral was set up to lure Andre.
In 2009, he had a heart attack, but survived.
On June 1, 2012, Stefano DiMera was shot dead from behind after several characters confronted him about his crimes
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