I am very curious about NBE for my wife, but I have some questions that hopefully someone can help me with. Although these herbs are safe, are they not increasing the levels of progesterone and estrogen? I know that progesterone can is necessary for inducing cell death and that it decreases the risk for several types of cancer. However, increased levels of estrogen are not good. Although estrogen (estradiol) may stimulate cell growth in the breasts, these cells may not die thereby resulting in cancer. I hope someone can shead some light on the subject. Are there only some herbs that upregulate estrogen production? Thanks for your time.