I've read recently that both damiana and papaya may actually supress progesterone. What do you think the significance of this would be for those of us PMS-type women who are taking vitex to promote progesterone? I wonder if we should stay away from these substances? Or perhaps just use them during the follicular phase when the body is estrogen dominant anyways?

I wouldn't take Papaya in large dosages because I have read it can cause infertility. That scares me because I still wanna have kids. Wonder if this is an urban legend though?