Jews were not spared in the Crusades:
On the way to the Middle East, they decided that only one of their goals was to wrest control of Jerusalem from the Muslims. A secondary task was to rid the world of as many non-Christians as possible - both Muslims and Jews. The Crusaders gave the Jews two choices in their slogan: "Christ-killers, embrace the Cross or die!" 12,000 Jews in the Rhine Valley alone were killed as the first Crusade passed through. Some Jewish writers refer to these events as the "first holocaust." Once the army reached Jerusalem and broke through the city walls, they slaughtered all the inhabitants that they could find (men, women, children, newborns). After locating about 6,000 Jews holed up in the synagogue, they set the building on fire; the Jews were burned alive. The Crusaders found that about 30,000 Muslims had fled to the al Aqsa Mosque. The Muslim were also slaughtered without mercy.
And of course the Spanish Inquisition targeted Jews, along with other "heretics".