It's been about a week now that I've been using Brava. My skin is less irritated. I wash the domes and my skin with Dr. Bronner's soap and I apply aloe gel to my skin 10 minutes before the domes and Benadryl or fragrance free Aveeno lotion at removal and after showering. I'm sleeping better. I take Tylenol PM. My measurements are still the same, but I feel a little fuller. My left breast especially didn't fill out the cup of my bra and that seems to be improving. This is becoming much more do-able.