Matt Damon - The Informant
Daniel Day-Lewis - Nine
Leonardo DiCaprio - Shutter Island
Morgan Freeman - The Human Factor
Viggo Mortensen - The Road

ORIGINAL PREDICTIONS

Leonardo DiCaprio: Shutter Island
Javier Bardem: Biutiful
Morgan Freeman: The Human Factor
Daniel Day-Lewis: Nine
Viggo Mortenson: The Road

Christopher Plummer... he's playing Leo Tolstoy in a movie with Helen Mirren. Sounds like Oscar bait to me. I mean, the Academy might think he's due for at least a nominations. Although, they have ignored him all these years, who's to say they won't continue.
Just thought I'd throw him into the mix.
-TAD

I agree with you Tad. I think Christopher Plummer is defiantly in the mix and has a great shot at both a nomination and possibly a win (the academy loves bio pics about tortured scholars, artists, and writers i.e. A Beautiful Mind). He probably won't start generating buzz till later in the year though.