I think a lot of it depends on your RE, your situation, and how many embryos you have. My RE proposed 5 day transfer for me because of concern around uterine rupture with multiples given that I have had extensive uterine surgery for fibroids. The thought is that best embryos will survive until day 5, so that fewer embryos will be transfered and the risk/chance of multiples is significantly reduced.
My actual decision to go to day 5 was made with RE on day 3 - we had 8 embryos on day 3 and 4 of them made it to day 5. If we had fewer, then we would likely have transfered what we had on day 3 and let it go from there.
cbsgirl
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