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Another thing I can think of is, PGD hurt your embryos

June 25 2012 at 7:00 PM
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  (Login miraclex2)


Response to New here and rambling...another try w OE/DE? (many losses, child ment)

You have 4 embryos PGD normal, and as far as I know, PGD has been proven to hurt embryos, since they are done on day 3 embryos. I am pretty sure that if you had 4 CCS or PGS normal embryos, you would have had at least one live birth (the number suggests so). You are not the first person that I read about with PGD normal embryos ending in CP, I have read way too many similar stories from older women.

I am thinking that you shouldn't do PGD at Zouves, it is not the best place for doing genetic testing. I myself debated a lot whether I should do day 3 PGS at my clinic since they just started offering it a few months ago, and I decided against being the guinea pig.

My strategy is, grow blast, and only transfer the highest grade blasts first, because there are researches showing that normal ratio is positively correlated with blast grading (not correlated with day 3 embryo grading). The normal ratio could be as high as 50% for our age group for the 5AA and 6AA, and it is a worthwhile bet.

Another thinking is, I know Zouves is VERY aggressive in his dosage. He gave me the most aggressive dosage among all my consults. High stim is known to cause more aneuploidy.

Just some food for thought.


    
This message has been edited by miraclex2 on Jun 25, 2012 7:02 PM


 
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Responses

  1. Re: Another thing I can think of is, PGD hurt your embryos - Anonymous on Jun 25, 8:33 PM
    1. 6.5 days of stim? You are doomed for failure! - MIR on Jun 25, 8:44 PM
      1. For 40+ age group, longer stim = good news - MIR on Jun 25, 8:47 PM
        1. Re: For 40+ age group, longer stim = good news - Anonymous on Jun 27, 4:30 AM
          1. yes, even mature eggs have different quality - MIR on Jun 27, 12:35 PM
      2. Re: 6.5 days of stim? You are doomed for failure! - oops, I can't count on Jun 25, 10:08 PM