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Actually this is not my point, I question the effectiveness of PGS

August 23 2012 at 4:46 PM
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MIR  (no login)


Response to That's what makes this journey so stressful. Even if you make it to

at this stage. I am not sure if the benefit outweighs the risk if my goal is shooting for a live birth, not avoiding miscarriage.

You need to make normals first, simple as that. CCS or PGS is no miracle so if my embryos are abnormal, they don't make them normal. But if my embryos are normal, there is a chance of PGS hurting them. If I have a whole bunch, then I don't mind losing a few in the process, but I don't.

Just look at the CCS number. For 41-42, the live birth rate per normal blast is only 37% (and that includes lots of highly fertile patients who manage to get twins out of it). Me, a subfertile patient, won't be looking at 37%, I will be looking at sub 30%. Then what is the point of testing anyway if the rate is so low? I might as well put one blast at a time to see what happens, which is what I am doing right now.

For the above 42 patients, the CCS results are downright devastating, and completely wipes out the need for genetic testing. The live birth rate per CCS normal blast is only 16%(!!!). I think most people on this forum who achieved live birth did it without genetic testing at all.

 
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