Yes, that's true

Yes -- my RE said PIO gives you about a 1% boost in success, but the main reason is that in women over 40, it can be more challenging to get the progesterone up and the PIO allows them to directly measure what is in your blood.

That's also why I think they are more comfortable doing PIO in the initial stages, when establishing the progesterone for transfer, but it's not as big a deal to switch to crinone later on. Also, isn't crinone expensive? I think my PIO is about $200 or $300 a month...maybe it all adds up to the same.

If I had neuropathy, I would do the crinone. I just have never really had any problem with the injections, though I don't love them, they have not been a super big problem.

BTW, my current doc will have me on the suppositories also starting after transfer in addition to the PIO...