I am on my 5th progesterone shot, and have been experience alot of pain/bruising. It is worst at night when I go to sleep. I am concerned also, that I am not injecting in the correct spot. Seems like everyone draws a different circle among nurses. Can anyone give me some guidelines, I need to aim for upper outer quad of buttock. When I pull back the syringe with PIO, it is very easy, does that mean I am not in the muscle. It was very hard to pullback the 1ml syringe with delestrogen, it just wouldnt budge. But the 3ml PIO syringe easily comes back, is that normal. I am injecting in the circle that they draw. Just looking for your feedback. Thanks!!