Without doing genetic testing there is no real way to know if your embryos are actually good. Even genetically flawed blasts can progress to pregnancies, at least that's the common explanation for incidental miscarriage. I have heard this number can be 50% but many factors influence this statistic. I could believe that failing with 2 good looking DE embryos is bad luck, but not say, four. That's my gut feeling, not a medical perspective.
I prefer PIO because I alway have breakthrough bleeding on supps and I never have with PIO, however this is not the case for the majority of patients. I also have no issue with injections and appreciate being able to quantitatively evaluate P4 levels. It's a personal decision in the end as they both are effective for the majority of women, and if you are not experiencing breakthrough bleeding then you don't have a specific issue with Crinone that would necessitate the change, but if you're into it then it's not going to hurt you at least. Just a warning, I've had to do PIO 2x a day which is really rough for a lot of people.
We are also going to do a scratch biopsy and I see a ME for elevated thyroid levels.
You are doing a lot to advocate for yourself. Thanks for the update.