We are actually having the same debate right now. I am mostly a "lurker" on this board. Our donor is set for retrieval on Saturday. This is our 2nd donor, we had 2 chemicals with our 1st donor cycle last year. My DH doesn't have any sperm issues but we are going to go ahead with the ICSI. We have been through so much both emotionally and financially that we would be devastated if we ended up with poor fertilization. I was thinking about the whole natural selection thing but I think in the end we want to do everything possible to get a bunch of good embryos.