This stuff sounds beyond eveil (potentially, anyway). I'll take it the day before, day of, and a few days following transfer. And if I start flipping out - I'll drop it ASAP. I have no interest in putting up with a hypo manic or manic episode.
On a related note, I do recall that Crinone sent me into a depressive, PMS-like tail spin (it is a vaginal progesterone cream). I had no idea why I was so darned depressed and impossibly cranky. It subsided once I went off of the Crinone.