Humira was prescribed 1st by my RE & then by the Beer Center. When my RE prescribed it, my test results were normal. (If I had better understood at the time, I would not have taken it.) When the Beer Center prescribed it, they were abnormal. That was 2 yrs. later. Yes, Humira is pre-cycle & the Beer Center would not clear my cycle to proceed until they were in normal range.
I really think you need to get Alan E. Beer's book "Is Your Body Baby Friendly?" It is really a comprehensive look at all of this. I was dealing with this going on 6 yrs. ago now, so my memory & my ability to parlay explanations accurately & clearly gets less & less, unfortunately. At the time I was trying to learn about things, I had a better grasp on who did what & the current state of things. Things can change a lot in 5 yrs., so I don't want to mislead you with stale information.
The other thing - and yes, this makes it all the more difficult - is that there is disagreement within the field over tests & treatments, so you will not find universal agreement over what to look at. At the time, the Beer Center & Dr. Kwak-Kim were the most comprehensive & that's what I - ever paranoid - wanted. I wanted to check into it all - blood-circulating NKs, uterine NKs, LAD/LIT, TH1/TH2, etc. Now, there are new names & I'm not sure what the current state of anything is. As much of a pain as the Yahoo board can be, those women (& occasionally men) are in the midst of it all.
I know you're looking for clear answers. I understand, truly. Unfortunately, there are often few clear, simple answers. My deepest, darkest fear was that there was something wrong with me no one would find or no one could find b/c science hadn't caught up yet. I honestly believed that was my fate, in truth. Still, there were certain things I wanted to rule out or cover before I threw in the towel & accepted that fate. Luckily for me, comprehensive immune testing & treatment DID work, although my initial attempts at it through my RE were not successful. There were completely logical reasons for that, I would learn in hindsight, but I still wasn't sure moving to an RI would help me as I still couldn't be 100% sure that was my only problem.
It's very hard & it's made harder still b/c of all the variables. Your body could be perfectly receptive to a pg., but you still need a normal embryo, which requires normal sperm & normal eggs.
Are the testing & treatment options perfected? No. Do the treatments always work? No. One of my board friends, who no longer posts, had that issue. She did everything, more than once, but tests repeatedly showed the treatment was not bringing her system into line.
It requires a leap of faith, no matter what.
What about a couple of 2nd opinions before you doing anything else? Dr. K has a lot of fans. From their descriptions, he is a doctor who REALLY cares & is meticulous about records review & going over options. (I haven't met too many REs who can be described so generously.) He is not an RI & is not too into that angle, but he succeeded with other "green girl" posters.
For those opening the link, there is mention of pg. & children, just fyi.
It's entirely possible you just haven't had a fair shot yet in terms of embryo quality. It's always impossible to know for sure, but esp. if the embryos are mediocre.
I know how hard you're trying & please know that it took me a long time, with many mistakes. Same with many others. The ease at which it may seem I & others say try this or that is rarely present for anyone at the beginning. It is hindsight that is 20/20.
I had back-up plans if the immune stuff failed, but luckily I didn't have to go there.
Maybe a couple of consults, one with someone versed in RI & one with somehow who is careful & not as closed off as many REs are, before deciding? Honestly, now that you've posted more & it's clear you've done some immune stuff, including IVIG, which is no small deal, I think you should really consider a couple of additional consults. A really good, thorough RE like Dr. K & someone well-versed in RI, like the Beer Center, Dr. Acacio, Dr. Scher, or Dr. Pace. Someone who will know all that stuff & be able to really look at what you've done & what you've tested for to determine what, if anything, more to do.
None of it is free, unfortunately, but I think if you narrow it down to 1 in each category, or someone who is truly comprehensive re. everything, it may prove to be very helpful.
Bharani, I've been working on this on & off all evening. I'm going to post it now. I hope it makes sense. If it doesn't, I'm happy to keep clarifying or offering other thoughts. But I'll post it now for what it is.
Most of all, please know I know how hard & confusing it all is. If there were one magic answer for all, I would happily post it, but there's not. So many variables come into play here. I know the feeling that throwing more money away is hard to stomach. I don't know where your dh is at right now with this, but mine was not pleased, so I get it's hard to sell spending more money for answers. Still, it can work out & it can be worth it, so don't despair. Hang tough! There are women here to help you out. I do think, though, you need a couple of comprehensive consults with doctors who will look at what you've done. Someone immune issue oriented for sure.
It's hard but stick with it. I can't even tell you how many tears I shed dealing with it all. And yes, I did it alone, too. I couldn't turn to my otherwise wonderful dh b/c he was so bitter & negative. So I did it all alone, with the help of women on these boards. Dh went along with me, but barely. You can do it!