I have a matching set...one each side. Try to alternate nightly so I am not lop-sided. Cooper said I will be on PIO for about 12 weeks. very expensive since I go through a bottle every 4 days.Ouch again....but worth it.last Wed progesterone was at 106 so it is working. I am haveing trouble keeping these patches in place with it being hot and me sweating. Tapeing them but that just irritates skin more.