I have had another failed cycle and this time I transfer more than the two previous time. Now, the thought of failing 3 DE's is very devastating. I saw my Re on Sunday. He wanted to do another cycle, but I have to do alot of stuff before I decid at least thinking where I will get the expense... and also I had myomectory, removed fibroid in July 2009. I haven't done any checking after that.
What do you think to do (HSG or hysterscopy) to check the uterus?
Any other thing you want to share.
Bharani , I am so sorry for what you are going through . For your testing I would go with hysteroscopy as it is a better test than HSG . I am planning to get that done myself . My RE repeats it every two years , even if nothing abnormal is found . Are you with a clinic with good success rates ? Is getting another opinion an option . You can try getting atleast a phone consult with one of the top RE's , if you are not with one already. You might get some good ideas that you maybe able to use wih your current RE . What is your RE's explanation for the lack of success ? What has been your specific issue , egg quality/uterine factors ? Would you consider immune testing for you and DNA fragmentation test for your dh(to uncover sperm quality issues).
I did twice the hysterscopy to remove small polyp. When I was doing own ivf. I did one DE cycle with my clinic but that donor was almost 33 yrs old and split cycle. Both of us, we didn't get pg. The re said it must be the donor since both recepient didn't get pg. In Canada it is illegal there aren't much donor. I have heard also it is illegal, I don't get it. Anyway, I couldn't get a donor sooner then I went to Syrcuse. It is reasonable cost and I learned from this board. It is horrible. The first time the donor made 4 which I was told 3 fertilized, but the day of transfer they said the 4th is there also. The re who did the transfer was honest. He told me not to keep my hope up. He said the embroyos are extremely bad 2-4 cells of day 3. Then, I did this cycle exactly after one year, but in between I had few cycle that didn't go through like finding the donor has hep in the middle of the cycle, another the donor had low estrogen around 30 and one follicle measuring 1 after 14 days of stim, another one ovulating (actually this is the one that I used it finally). I spent so many dollars for outside monitoring.
So, I also think I didn't get a good doctor yet. And I hope that is the case. I will ask the hysterscopy. My re said the HSG and x-ray. I will what he will advise.
Just wanted to ask was this cycle a total negative or was it a chemical. I'm wondering if the anonymous post below was you. Sorry to ask but if it was a chemical it makes a big difference to your next course of action as a chemical shows that you did at least have implantation.
make any difference for future cycle? Yes, it was me and I didn't want to be negative person. Which I was all this time. In 40+ board. Went to that board not because of my age but the re kept saying your fsh is like woman in their 40+. I used to hang around there and now here.
I did email you and kept waiting for your respond. I felt that you didn't want to give negative comment and since I was in the middle of the cycle maybe you said you can't help. Anyway, I am done with them. I have to look another place and take my time.
the re who transfered said they were extremely poor and not to keep my hope. They were 2-4 cells on day 3. So they weren't where they are supposed to be. And I feel they were dead or almost dead.
And the other cycle with the same clinic. The re said they are 6-8, they are good. But said it quickly as if he didn't want to talk about it. He then left the room. I asked the nurse if I can ask the embroyologist. She said usually is the re who give the answer. So, I felt uneasy to request again.
Unfortunately, the picture I left in my dh car. When dh comes back I will post it. But three other embroyos didn't make it to be frozen.
I too had three fresh DE cycles fail, then followed with an FET from the third cycle that failed too. Its beyond heartbreaking when what SHOULD be the magic answer doesnt fill our arms and there arent any answers.
Talk with your RE and get a plan in place- do the hysteroscopy, and see if there is anything else you can change/add - immune testing, DNA frag testing on the sperm, adding steroids, etc.
Again, I am so sorry, I know how you feel and it sucks.
" Some people built castles in the air. She constructed hers from mashed potatoes, which kept down demolition costs." Sarah Sloane, Borrowing Priviledges
How is the procedure? I did once, and that time is they removed a polyp, they put me sleep. It was like serious procedure. The other time, my current re removed polyp again but I was awake. I think he said he did hysterscopy. But it was painful.
How was yours?
I am sorry the cycle did not work.
Yes, I think you should do the test..My RE insited on a HSG after a myomectomy..just to be on the safe side. Ended up, I did need additional surgery to clean up some scar tissue. I would do it..you just never know.
Wish it could have turned out differently for you and really hope you can manage the finances to continue.
Oh Bharani, I am so sorry for you. I cant believe it was negative again. Where do you get your strength to go on? I was soo done after this cycle if it didnt work out after 2.
You are in my prayers, however I have no advice since I dont know about it.
All this time I never had a cycle that satisfies me and failed. Particularly #2 I feel they put back almost dead embroyos. Because they were 2-4/6 cell in day 3. I think they were 2-4. And the first time, the donor was 33 yrs old and it was split. So the other donor didn't get pg also, and that one was a FET. Because I had fibroid and kept bleeding till day 10, so I had to do a fet.
I am so sorry. You have been through so much. If it were me, I would do a hysteroscopy rather than an HSG to really check out what is going on in the uterus. They can do them in office while you are awake (which I found very painful) if they are not thinking they are going in there to actually remove something. That way they can find if anything is there and schedule you for a hospital procedure if needed. I would also change clinics if at all possible. I think all of your DE failures have been at the same clinic right? Based on what I have read you post it doesn't sound like you have ever had a really good shot with any of the cycles so it may be nothing to do with your uterus. But it is always good to check everything out again if it has been awhile. Best of luck next time and I am so sorry.
how are you? I have been thinking about you. In the future, I think I will go your clinic. But they don't respond, what is wrong with them? I know you said they are good? I just feel unease about doing another even very far DE cycle. How are they coordinate the cycle? My current clinic was horrible in it.
No, my de's were in two different clinic. 2 and 3 were the same clinic.
I will keep in touch with you.
...it is so unfair and so frustrating to not have answers. (((HUGS))) I agree with the previous posters about looking into everything. After one BFN on fresh DE cycle and chemical on FET I'm going to insist the RE look at everything before we transfer our last embryo. It sounds like you have had a difficult time finding a good donor. Do you have the option of using a proven donor? Good luck moving fwd and take care.
because of my ethnic, my complexion is rare. Only the first donor, who was old 33 yrs, shared the similarities. The other two were olive tone but not my etnic. Honestly, I said the first time I moved to de I don't mind..it is just dh who has hard time. And it is difficult to get someone who has the same colour tone,...etc
I had several DE failures as well, and I was young with unexplained infertilty. It was a terrible time. In the end, a very proven donor worked for me. Perhaps its not you, but the eggs. I'm so very sorry. Big hug - I've been there.