Please help...when you were on the pio do the lumps stay long? I tried the ice before heat after, and they aren't going anywhere. They feel like a half of hard boiled egg(maybe a little more) on both sides...and was wondering also if the medicine can get around your system with these bump things. Also having itching and bruising from the del estrogen?
Also this one really puzzles me...the cramping. I had the cramping all along not anywhere near the transfer, and still had it.
Sorry I remember posts before on some of this, but my search is acting up again, and I do not remember reading about the circulation thing.
Thanks for listening and any help would be really appreciated

Yes, I got those and, unfortunately, they did last a while. I was taking a different kind of PIO shot that you take every 3 days. For me, the bumps got worse as time went on (I suspect I was developing a sensitivity to something in the shots). When are you seeing your doctor again? Can you ask if there's an alternative? Maybe Crinone to take vaginally?

I'm not sure what you mean by the estrogen. I took estrogen orally.

Best of luck to you.

For the reply. I take the PIO every single day! The del estrogen is every third day. I do not know which one is causing the bumps or the itching...but maybe both. Did you have cramping from the first part of these PIO shots? Maybe the del estrogen is causing the cramping? Oh heck I am freaking out a little trying to get this all straight...I know my moods are all over the place

I had terrible lumps from the PIO. It's been 4 weeks since my last shot, and I still have a small lump on one side, but it doesn't hurt. I also had the delestrogen 2x/week, but I don't remember any problems with it. I did have some cramps around the time of my beta and for a couple of weeks after.

I posted this before to someone else, but if you start having itching and redness at your injection site, talk to your clinic about changing the medium for your PIO. I started with sesame oil and had to switch to olive oil. Even that started to make me itch after a while, but then I was nearly finished with the shots.

Good luck. It really is all worth it!

with my injections (soreness for days), but I got some great advice from the ladies on the board that worked. First, when it came to the shots themselves, during my 2nd cycle, I had the nurse at the clinic draw on me (with a marker) the site where I was able to inject, and interestingly enough, it was about 4 to 5 times the size of the area where my husband had been doing my injection. So I had a lot bigger area with which to work, so I would not inject the same area often. I also alternate sides with the shots. Of course, on the day that you have 2 shots, you'll be doing one side 2 days in a row, but again, moving those shots around is key.

Then when it comes to icing, I increased the time. I had been estimating and doing about 2 minutes, I now watch the clock and I do at least 5 minutes, sometimes up to 7. Then afterward, I had been doing a warm washcloth on the area for a few minutes, but I switched to a heating pad for about 20 minutes . It's like the heat melts the lump away. Then after the heat, I might massage the area a bit, and that's pretty much it.

The other big thing that the ladies told me, that took me forever to embrace, was that for those who did the shots themselves, the pain was less and the lumpiness also decreased. I can't explain why, but that has been the case with me. I started doing the shots myself when my husband was out of town for 2 weeks (which I did kicking and screaming, by the way...I was a HUGE wimp about doing the shots myself). After he came back, I wouldn't let him do the shots anymore. In fact, there are times when I don't even do the heat after the shots because I've noticed that I can do several days worth of shots now without the lumpiness, and of course, the process is very time consuming.

I hope you find relief soon, because I know it can be tough giving yourself the shots (although I am sure you will) when you know the pain and lumpiness that will follow.

While I iced the injection spot, I would also have a heating pad heating the shot. Sometimes the shot would get hot and it would only take a minute or two for it to cool down.
I also iced for 20 mins or so...and I felt nothing. I didn't really heat after, just massaged the area.
Having the nurse draw at the circle is really helpful, or at least having a drawing to show you where. My husband got 'off course' for a week or so and that is the only time I got lumps...it needs to be on the higher side of the buttock.
Good luck.