Numbers were good for prog ect, lining good ect.
Followed instructions. Had blockedtubes removed
thinking that would be the answer. Still negative
a second time with DE.

4 (c)'s in freezer. Maybe I should give it another
shot. The A's didn't work fresh, B's didn't work how
could the C's possibly succeed?!

What can I do? I Have dd 17yrs old so I have been
capable of an easy successful pregnancy. I feel
like my body is toxic now.

Any help appreciated.

Issla

The Beer clinic is one that you can google to get info from if you think you have immune issues but I do want to point out that some of us start out with very low betas. Mine was only 37 on 15dpo, so I'd have also had a negative on 13dpo if I'd poasd. Stay on your meds. You may just have a slow initial start. I hope that will be the case for you. Best of luck.

I'm sorry that it's still negative. ...I don't want to give false hope, but I only had the faintest of lines on day 13's poas after I retrieved it from the wastebasket late in the evening. ...the faintest of lines on the morning of day 14... had a beta of like 33. I'm still hanging in there... 7 1/2 months along right now.

I'll keep my fingers crossed for you. But yes, you should do as much testing as you can to give those last embies the best chance if you need them! There's also just being on the bad side of the statistics... I hated that answer, but it does seem to be true sometimes when everything else looks good.

Best wishes!

I asked for an earlier beta, tomorrow (1 day early) so I can get the bfn and go to next step....
Whatever that is. I won't give up till I get the official word. Then I'm going to look into
other issues that may be interfering with implantation.

Thank you for support:)

Issla

I think if you google reproductive immunology, you will see Sher, Beer and SIRM listed. In CA, I am working with Dr. Acacio at Acacio Fertility, he used to be with SIRM in Org Cty/Los Angeles, and I have been very happy with his knowledge and advice regarding immune issues.

Minniet,

I'm in GA. The only doctor that I have heard of regarding this is
Toth and from what I understand his practice is a little controversial.
Googled GA for clinics that would specialize but came up wit nothing.

Made an appt with GI to check for Celiac disease and read that my RE
can test for AA and NK. If you have any thoughts on this please let me
know. I'm afraid to cycle again without answers to why no embryo will take.
I guess I may never know and may never be successful.

I do plan on looking into clinics you mentioned.

Thank you!!


I

Why don't you just call Dr. A's office. He is incredibly nice. You can ask for a consult (I think they may do free first consults for Resolve members) and he ACTUALLY WILL READ your chart. (This was a first for me, at least. Every other RE I met skimmed mine and mixed me up with others) He kept a copy and gave me a copy of mine back ( my chart is now about 2 inches thick), and I swear, the man actually opened up to certain pages and quoted things back to me.

His head nurse, Sylvia, is also really on the ball. She won the Resolve best IF nurse in the US, and she leaves no detail behind.

I did a consult with him just to rule him out, but I was so impressed, I am working with him now. Of all my local friends, he has gotten most everyone pregnant who had suffered numerous failures elsewhere.

Just try a call.

Sending you good wishes on your search.

PS I have not seen Toth, but I also feel he is too unorthodox. I like that Acacio seems to have been personally involved in studies or can quote them about why he does certain treatments.

But you can see my history here and on the green board, I have seen a lot of docs and tried a lot of things.

I remember you from pink board, so I know you've been
through a lot. I'm just trying to rule out possible things
that could be a problem for implantation. It may be the egg/sperm
combination. Is it possible that these embryos are just not
compatible with my body ?


Will let you know about DR. A.

Thanks again !
I

Does celiac disease effect implantation rates?

I don't know the answer to that question, but it may. Do you have it under control? What are your flares like? I imagine that untreated celiac would make it harder for implantation to occur, there would be great systemic inflammation.

I have a wheat sensitivity but do not have celiac myself.

Trying to rule things out. Looking at symptoms, maybe I've had
a few....total. I doubt I have it but I've met my insurance decuctable
and it's getting to the end of the year so why not!

If there is anything else that should be tested, let me know:)

Don't stop your meds til you do blood betas! Good luck hoping and praying for the best outcome LMD

Thinking of you and really hoping for a good result for you.
TAke care
pict

I had six miscarriages and 2 failed IVFs when going through UCSF. They just did basic autoimmune stuff. I begged them to at least put me on Heparin, baby aspirin or something... but even after already having six miscarriages (6-8 wks) they said I'd have to have one more before they'd consider it.

I did get pregnant again with OE and actually got prednisolone own my own because I'd heard it had helped many women in Europe. Sure enough I made it to 24 weeks for the first time ever - only to lose my dear daughter to a rare genetic anomaly. It was very bad luck, indeed... but the prednisolone helped me get past that tricky autoimmune early miscarriage time.

Unfortunately I was unable to get pregnant again on my own. Soon after I lost my daughter my FSH jumped from 9 to 27 and it never came down again.

Thank goodness we went to Dr. Zouves! He did a FULL autoimmune workup on me and found several things:

1. I had elevated natural killer cells
2. I was homozygous (had two copies) of the MTHFR gene mutation (causes thrombosis, i.e., clotting issues and women with this have a far greater chance for multiple miscarriages)
3. Antithyroid antibodies

When I did my DE transfer this time I was put on Lovenox injections and prescription Folgard for the MTHFR, got intralipid infusions at the Beer Center (arranged by Dr. Zouves) for the natural killer cells, got my thyroid meds adjusted... AND Dr. Zouves has kept me on a prescription of dexamethazone similar to the dosage of prednisolone I had taken the only time I was able to sustain a pregnancy (I'm weaning off that within the next few weeks).

While getting my intralipid infusions I have heard so many miracle stories from women with similar autoimmune problems - either diagnosed through Dr. Beer's (or his successor's office) or Dr. Zouves. The place is filled with pregnant women and many had gone through so many miscarriages/failed cycles until they found doctors who understood these autoimmune issues. Some other clinics scoff, but these treatment protocols can make a difference! Now, is it an answer for everyone? No. Not everyone has these issues... but darn it! If we've had repeated problems we should be tested!

I'm happy to say I'm 11 weeks pregnant from my first DE transfer. I only wish I had gone to Dr. Zouves years ago.

Good luck!