I can't tell you about the hormone therapy, but in 2003 I had a bone marrow transplant to rid myself of leukemia.I've been through full body irradiation and high dose chemo. It wasn't fun, but it's do it again in a heartbeat under similar circumstances.
Feel free to contact me if you want some honest answers from someone that went through it.
The biggest side effect for me is the mental one. Illness and injury are weighed on a whole different scale.
Oh and most importantly...no more cancer, drugs, or doctors for me since ~2008